The Key Issues Related to Features and Perspectives of Antioxidants in Asthma and Allergy Pharmacotherapy

Authors

  • Nana Gorgaslidze Department of Social and Clinical Pharmacy Tbilisi State Medical University Tbilisi Georgia Author
  • Ia Pantsulaia Department of Immunology Tbilisi State Medical University Tbilisi Georgia / V. Bakhutashvili Institute of Medical Biotechnology Tbilisi State Medical University Tbilisi Georgia Author
  • Marina Giorgobiani Faculty of Public Health Department of Hygiene and Medical Ecology Tbilisi State Medical University Tbilisi Georgia Author
  • Nodar Sulashvili Scientific Research-Skills Center Tbilisi State Medical University Tbilisi Georgia Tbilisi Georgia / Pharmacology Direction of International School of Medicine Alte University Tbilisi Tbilisi Georgia / Faculty of Medicine Sulkhan-Saba Orbeliani University Tbilisi Georgia / Pharmacy Program at Shota Meskhia Zugdidi State University Zugdidi Georgia / School of Health Sciences University of Georgia Tbilisi Georgia Author

Abstract

DOI: 10.52340/GBMN.2023.01.01.23 The review aims to highlight the anti-allergenic and anti-inflammatory potential of some antioxidants in the pharmacological treatment of asthma and allergies. Under various physiological and pathological conditions, oxidative stress is both a result of and a contributor to redox metabolism. To effectively manage existing issues, it may be essential to understand the molecular mechanisms of basal oxidative stress and the role of antioxidants. It has been demonstrated that antioxidants can change the biomarkers of allergic inflammation and other consequences of allergy. Antioxidants can neutralize free radicals and control the level of cholesterol and other lipids in the blood. Antioxidants have anti- cancer activity due to prevention and inhibition of cancer cell growth. Antioxidants stimulate and activate the regeneration of normal, healthy cells. The complexity of each response and the multiple physiological effects complicate clinical studies of antioxidant therapy. Based on the existing evidence, we believe that antioxidants like zeolin-containing Geomin Forte have promising perspectives as adjunctive pharmacotherapy for asthma and allergic diseases.
First page of the article: The Key Issues Related to Features and Perspectives of Antioxidants in Asthma and Allergy Pharmacotherapy

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Published

2023-04-22

How to Cite

Gorgaslidze, N., Pantsulaia, I., Giorgobiani, M., & Sulashvili, N. (2023). The Key Issues Related to Features and Perspectives of Antioxidants in Asthma and Allergy Pharmacotherapy. Georgian Biomedical and Medical Nexus, 1(2), 64-67. https://gbmn.org/article/view/203