Technology and Composition of Saperavi-Based Cosmetic Emulgel

Abstract

Background: In recent years, wine has gained increasing recognition as a functional food product that is essential for the treatment and prevention of various kinds of diseases. Saperavi grape variety, which has a high concentration of phenolic compounds, is particularly noteworthy from the perspective of its application in cosmetology practices. Objectives: In this research, we have determined the recipe and developed the technology of the cosmetic emulgel that contains wine and oil of the Georgian grape variety "Saperavi." Methods: Modern pharmaco-technological, biopharmaceutical, physicochemical, and structural and mechanical methods were used in the research. The pH of the aqueous fluid extraction of the researched emulgels was determined by the potentiometric titration method. The osmotic activity of emulgels was determined by the gravimetric method. The colloidal stability of emulgels was determined on a laboratory centrifuge. The rheological characteristics of the composition were studied on a Viscometer RVDV-1 T. Results: Based on biopharmaceutical studies, the recipe of Saperavi emulgel was developed with the following composition: saperavi wine 20.0 g, carbopol 940 - 1.5 g, propylene glycol - 5.0 g, glycerin - 5.0 g, Saperavi grapeseed oil - 5.0 g, Tween 80 - 1.0 g, sodium hydroxide - 0.8 g, sorbic acid - 0.45 g, potassium sorbate - 0.15 g, purified water up to 100.0 g. Using Saperavi emulgel on the clean facial skin of volunteers for 21 days led to a sharp reduction in oiliness, cleansing of pores, reduction in the number of keratinocytes, and noticeable whitening of pigment spots. Conclusions: Overall, the Saperavi wine cosmetic emulgel formula and technology have been developed through this study. Additionally, the developed emulgel demonstrated some therapeutic benefits on volunteers' skin.